george nisyrios | HIV
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Aug 10 2016

Of mice and then men

Drug development typically follows a path from theory and concept, to drug/chemical/biological production, to test tube testing for in vitro efficacy, to animal testing to early phase I first in human testing. A crucial step in understanding the behaviour of a drug and safety analysis before...

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Aug 10 2016

Working in a Phase I trials unit

A few months ago I started working for a Phase I clinical trials unit as a medical officer/sub-investigator after 17 years in clinical practice. What is a Phase I study ? A Phase I study is usually a first-in-human study of a new experimental medication in healthy volunteers. ...

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Sep 24 2015

Travelling (or not) with HIV

Quite a few times a year, I will have a patient walk in and tell me they have booked an overseas holiday. The first thing I say is "where" and this is often followed by "I don't think you can go there". Imagine that - being told you can't travel...

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Sep 22 2015

The dream of an HIV cure.

Most people with a bad medical problem want to be cured.  Take cancer as an example.  Of course this does happen for some lucky people.   But many medical problems are effectively treated and affected persons achieve a pretty good quality of life.   The drive behind finding a...

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